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Table 1 PRECIS-2 ratings to demonstrate the extent of pragmatism in the trial design immediately following the pilot study

From: Barriers impacting the POINT pragmatic trial: the unavoidable overlap between research and intervention procedures in “real-world” research

Domain Scorea Rational
Eligibility criteria 4 All patients with opioid-related issues are study eligible except those who are not able to provide informed consent by the time of ED discharge.
Recruitment path 5 Patients are recruited when they are present in the ED or on an inpatient unit if they were admitted there from the ED.
Setting 4 The trial is occurring in university-affiliated teaching hospitals; however, the specific EDs do not regularly engage in research.
Organization intervention 3 The research grant provides the hospital with funding and resources to implement and run the intervention; however, the hospital employs and supervises PRCs.
Flex of experimental intervention delivery 3 PRCs are given guidelines for how to engage patients, but implementation of guidelines is not regularly monitored.
Flex of experimental intervention adherence 5 Patients are not expected to adhere to the intervention; rather, it is up to the PRCs to engage and motivate them.
Follow-up 5 All follow-up data collection is through existing administrative sources.
Outcome 5 Primary outcomes are (1) treatment linkage, (2) treatment engagement, (3) reduced overdose, and (4) reduced overdose mortality, which are all relevant to people in OUD recovery.
Analysis 5 An intention-to-treat approach is followed.
  1. a1/very explanatory, 2/rather explanatory, 3/equally pragmatic/explanatory, 4/rather pragmatic, and 5/very pragmatic